By John Fawcett Wilson (auth.), John Fawcett Wilson (eds.)
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Extra info for Drugs Eicosanoids: Second Messengers. November 1995
Wt. 9 Digoxin is a glycoside obtained from the leaves of Digitalis lanata. It is used in cardiac failure to increase the force of myocardial contraction and in supra-ventricular arrhythmias where use is made of its ability to reduce the conductivity of the heart. 0 ng/ml. Digoxin binds strongly to tissues such as skeletal and cardiac muscle with a resulting large volume of distribution and a long half-life in plasma of 20 to 50 hours. Steady-state plasma concentrations take 6 to 7 days to be achieved.
Plasma level monitoring is used as toxic symptoms can be difficult to distinguish from those of underdosage. The therapeutic range in plasma is 10-30 ng/ml. 0 © KLUWER ACADEMIC PUBLISHERS 1995, ISSN 0926-2067 1510 THE IMMUNOASSA Y KIT DIRECTORY, SERIES A, VOLUME 3, PART 4 (DRUGS; EICOSANOIDS; SECOND MESSENGERS) DIGITOXIN m Boehringer Mannheim Cat. /Trade name: 1288903/Enzymun-Test Digitoxin DIGITOXIN II Du Pont Cat. 001% Precision: Within batch: Not quoted Limitations: Expected values quoted for: Normal therapeutic range Number of references: 1 Sensitivity: Specificity: The following analytes are known to cross react: Digoxin, dihydrodigoxigenin, dihydrodigoxin, dihydrodigitoxin, digoxigenin, digitoxigenin, digoxigenin-mono-digoxoside, digitoxigenin-monodigitoxoside, digoxigenin-bis-digitoxoside, digitoxigenin-bis-digitoxoside.
0 *The sample cup should hold 100 1-11 more than the total volume required for the tests **Two-week calibration curve stabili © KLUWER ACADEMIC PUBLISHERS 1995, ISSN 0926-2067 1514 THE IMMUNOASSA Y KIT DIRECTORY, SERIES A. I Incstar Corporation Cat. /Trade name: CA-1525/GammaCoat@ Assay type: RIA Detection: Radioisotopic Format: Tube. 0 15 minute STAT procedure © KLUWER ACADEMIC PUBLISHERS 1995, ISSN 0926-2067 THE IMMUNOASSA Y KIT DIRECTORY, SERIES A. VOLUME 3, PART 4 (DRUGS; EICOSANOIDS; SECOND MESSENGERS) DIGOXIN DIGOXIN II Bayer Diagnostics CAS 20830-75-5 1515 Cat.
Drugs Eicosanoids: Second Messengers. November 1995 by John Fawcett Wilson (auth.), John Fawcett Wilson (eds.)