By Christoph Scholtissek, B.M. Richards, R. Vendrely, C. Vendrely, D.P. Bloch
The box of nucleic acids has grown to the sort of tremendeous dimension that it's very unlikely to incorporate all guides about the chemistry and organic function of nucleic acids in a piece of writing of the size awarded during this "Volume. for that reason, it can be crucial to choose an important contributions and people now not incorporated "in famous experiences. in lots of situations reference is made purely to the authors who summarized their really good box in chapters of the 3 volumes of "The Nucleic Acids" (edB. E. CHARGAFF and J. N. DAVIDSON, Acad. Press, manhattan 1955 and 19(0) or to the "Nucleic Acid Outlines" (V. R. POTTER, Burgess Publishing Comp. Minneapolis), the place additional literature and extra unique discussions can be stumbled on. proof and theories may be handled, yet now not lists of references. accordingly it isn't attainable to persist with in all circumstances the ancient improvement of an concept and to admowledge all guides that can be very important and inter esting from one other viewpoint. little or no is pointed out approximately equipment within the box of nucleic acids.
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Additional info for Chemistry and Cytochemistry of Nucleic Acids and Nuclear Proteins
In: CHARGAFF and DAVIDSON, The Nucleic Acids II, Academic Press: New York. 93-153. EDSTROM, J. , and W. BEERMANN, 1962: The base composition of nucleic acids in Chromosomes, puffs, nucleoli, and cytoplasm of Chironomus salivary gland cells. J. Cell BioI. 14, 371-380. , and A. RICH, 1957: Studies on the formation of two- and threestranded polyribonucleotides. Biochim. Biophys. Acta 26, 457-468. , 1963: Molecular memanism of mutations. 207-269. - E. BAUTZ, and E. BAUTZ-FREESE, 1961: The Chemical and mutagenic specificity of hydroxylamine.
1955), McMASTER-KAYE (1960), and others, concerning possible precursor relationships of nucleolar and chromosomal RNA and the localization of their synthesis. Although the nucleolar RNA is synthesized sometimes faster, sometimes slower than the chromosomal RNA, it seems that the nucleolar RNA is made first around the organizer and spreads later over the whole nucleolus (PELLING 1959). The results obtained with fowl plague virus-infected L-cells (see above) favour the idea that the nucleolus rather stores some RNA, whim is made at the DNA of the organizer, ,than that it is an RNA-synthesizing center of its own.
I-amino isobutyric acid 3 34 V/3 a: C. SCHOLTISSEIt, The Chemistry and Biological Role of Nucleic Acids enzyme in rat liver whim removes specifically the last three nucleotides and adds them again i n v i t rounder suitable conditions. A high turnover of only the last nucleotide of this transfer-RNA in rat liver in v i v 0 has been found by SCHOLTISSEK (1959, 1960, 19(2). In yeast similar results have been obtained by RossET and MONIER (1963). A review on the function of the transfer-RNA has been given recently by BERG (1961).
Chemistry and Cytochemistry of Nucleic Acids and Nuclear Proteins by Christoph Scholtissek, B.M. Richards, R. Vendrely, C. Vendrely, D.P. Bloch