By Zhongping Tan, Lai-Xi Wang (eds.)

ISBN-10: 1782623337

ISBN-13: 9781782623335

ISBN-10: 1782623825

ISBN-13: 9781782623823

ISBN-10: 1788011228

ISBN-13: 9781788011228

Glycans play an essential function in modulating protein constitution and serve as from involvement in protein folding, solubility and balance to law of tissue distribution, acceptance specificity, and organic task. they could act as either confident and adverse regulators of protein functionality, offering an extra point of keep watch over with admire to genetic and environmental conditions.Due to the complexity of Read more...


This ebook describes the advance and alertness of glycoprotein and glycan synthesis applied sciences as instruments for knowing and manipulating protein glycosylation. Read more...

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119 The surface plasmon resonance (SPR) binding analysis of the interactions between the synthetic isomeric M6P glycoprotein glycoforms and the cation-independent mannose 6-phosphate receptor (CI-MPR) reveals that a single M6P moiety located at the low α-1,3-branch of the oligomannose context is sufficient for high-affinity binding to receptor CI-MPR, the presence of a M6P moiety at the up-branch of the oligosaccharide core is dispensable, and close proximity of two M6P-oligosaccharide ligands in the peptide/protein context is critical to achieve high affinity for the CI-MPR.

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Chemical biology of glycoproteins by Zhongping Tan, Lai-Xi Wang (eds.)

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