By Joint Formulary Committee
The British nationwide Formulary (BNF) is your crucial reference publication for prescribing, shelling out, and administering medicinal drugs.
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The dangers of other Controlled Drugs are less clear because recognition of dependence is not easy and its effects, and those of withdrawal, are less obvious. To see that the patient does not gradually increase the dose of a drug, given for good medical reasons, to the point where dependence becomes more likely. 1). The prescriber should keep a close eye on the amount prescribed to prevent patients from accumulating stocks. A minimal amount should be prescribed in the first instance, or when seeing a new patient for the first time.
This has led to the use of portable continuous infusion devices, such as syringe drivers, to give a continuous subcutaneous infusion, which can provide good control of symptoms with little discomfort or inconvenience to the patient. Syringe driver rate settings Staff using syringe drivers should be adequately trained and different rate settings should be clearly identified and differentiated; incorrect use of syringe drivers is a common cause of medication errors.
The risk of osteonecrosis of the jaw is substantially greater for patients receiving intravenous bisphosphonates in the treatment of cancer than for patients receiving oral bisphosphonates for osteoporosis or Paget’s disease. All patients receiving bisphosphonates should have a dental check-up (and any necessary remedial work should be performed) before bisphosphonate treatment, or as soon as possible after starting treament, see also Bisphosphonates: Osteonecrosis of the Jaw, p. 499. For cancer patients taking bevacizumab or sunitinib, see also MHRA/CHM advice (Bevacizumab and sunitinib: risk of osteonecrosis of the jaw), p.
British National Formulary by Joint Formulary Committee