By Joachim W. Fluhr, Peter Elsner, Enzo Berardesca, Howard I. Maibach

ISBN-10: 0849314437

ISBN-13: 9780849314438

Bioengineering of the surface, or extra exactly the biophysical overview of dermis body structure, is relocating swiftly from a descriptive method of a deeper realizing of biophysical and biochemical procedures. This moment version of the preferred textual content Bioengineering of the surface: Water and Stratum Corneum displays the growth within the box, concentrating on the dramatically superior realizing of pores and skin body structure. particularly, it stories the shift in our realizing of the stratum corneum from an inert surrounding sheet to a biologically energetic compartment.

The stratum corneum is the interface among the occasionally harsh surroundings and the inner turmoil of the human physique. in accordance with plenty of contemporary courses, this ebook explains the mechanisms all in favour of stratum corneum barrier functionality and hydration. It displays 10 years of development not just of the non-invasive biophysical evaluate of epidermis body structure parameter, but in addition of the perfection of the to be had units. It brings all learn on epidermal water and transepidermal water loss in wellbeing and fitness and sickness up to date with the revision of present chapters in addition to extra chapters from new participants on hydration and itching. This variation additionally comprises new guidance at the standardization of measurements.

Bioengineering of the outside will improve conversation in the study group and should be worthwhile for scientists within the dermis bioengineering box via featuring tools that supply trustworthy and reproducible ways for product trying out within the pharmaceutical and beauty industries, in addition to for uncomplicated learn

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Additional info for Bioengineering of the Skin: Water and the Stratum Corneum, 2nd Edition

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Dermatologica, 176, 65, 1988. 11. , Water-keratin interaction in human stratum corneum, Bioeng. Skin, 3, 227, 1987. 12. , Water sorption by human callus, Biochem. Biophys. Acta, 540, 518, 1978. 13. , Bound water in stratum corneum measured by differential scanning calorimetry, J. Invest. , 59, 225, 1972. 14. R. , Plenum, London, 1972. 15. L. , Multilayer adsorption of moisture in wool and its application in fabric steaming, Text. Res. , 62, 648, 1992. 16. , Water in keratin: study of the depolarization thermal current peak.

According to Hey et al. 3 Å when the relative humidity reaches 65%. They logically concluded from this result that, in this relative humidity range, the water is located between the keratin microfibrils. We have shown that more water penetrates the structure in the high relative humidity range when lipids are removed. This last result, combined with the x-ray results of Hey et al. [12], means that a certain number of lipids are likely to be located inside the corneocytes. This agrees with one of the conclusions reached by Goldsmith and Baden in 1970 [30]: WSM could be an important element in water binding, but the most important phenomenon observed during their extraction was the considerable limitation of the equilibrium kinetics between SC and the atmosphere.

45. A. et al. The lipid organization in the skin barrier, Acta Derm. , 208, 23, 2000. 46. A. et al. pH, cholesterol sulfate and fatty acids affect stratum corneum lipid organization, J. Invest. Dermatol. Symp. , 3, 69, 1989. 47. A. et al. Human stratum corneum polar lipids and desquamation, Arch. Dermatol. , 277, 284, 1985. 48. W. et al. Lipid composition of cohesive and desquamated corneocytes from mouse ear skin, J. Invest. , 86, 187, 1986. 49. , A new look at the ichthyoses: disorders of lipid metabolism, Pediat.

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Bioengineering of the Skin: Water and the Stratum Corneum, 2nd Edition by Joachim W. Fluhr, Peter Elsner, Enzo Berardesca, Howard I. Maibach


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