By Wafik S. El-Deiry

ISBN-10: 1592598544

ISBN-13: 9781592598540

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Cell. Biol. 116, 247–254. Schmieder, R. , et al. (2001) Effect of the angiotensin II type 2-receptor gene (+1675 G/A) on left ventricular structure in humans. J. Am. Coll. Cardiol. 37, 175–182. , et al. (2001) Angiotensin II type 2 receptor is essential for left ventricular hypertrophy and cardiac fibrosis in chronic angiotensin II-induced hypertension. Circulation 104, 346–351. Bloem, L. , Foroud, T. , Ambrosius, W. , et al. (1997) Association of the angiotensinogen gene to serum angiotensinogen in blacks and whites.

5) in comparison with control. This study demonstrated that intramural delivery of advanced c-myc neutrally charged antisense morpholino compound completely inhibits c-myc expression and dramatically reduces neointimal formation in a dose-dependent fashion in a porcine coronary stent restenosis model while allowing for complete vascular healing. 3. 1. Phosphorylcholine Matrix for Drug Delivery Phosphorylcholine stents were loaded with AVI-4126 using soak-trap (ST) and dry-trap (DT) methods. Twelve pigs underwent AVI-4126 phosphorylcholine coronary stent implantation (three stents/animal).

Nucleic Acids Res. 31, 589–595. 60. , Elbashir, S. , et al. (2003) Sequence, chemical, and structural variation of small interfering rnas and short hairpin RNAs and the effect on mammalian gene silencing. Antisense Nucleic Acid Drug Dev. 13, 83–105. 61. 61 Elbashir SM, Harborth J, Weber K, Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 2002; 26: 199–213. 62. MaManus, M. , Haines, B. , Chen, J,. and Sharp, P. A. (2002) SiRNA-mediated gene silencing in T-lymphocytes.

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Antisense Therapeutics by Wafik S. El-Deiry

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