
By Alexander M Vaiserman (ed.)
ISBN-10: 178262435X
ISBN-13: 9781782624356
ISBN-10: 1782626603
ISBN-13: 9781782626602
ISBN-10: 1782629858
ISBN-13: 9781782629856
Presents an summary of present learn aimed to go looking for life-extending medicines and describes pharmacological points of anti-aging drugs. Readers are brought to the ancient historical past of geroprotection within the first bankruptcy. In-depth info on types for investigating geroprotective medicinal drugs precedes a bit masking anti-aging houses of pharmaceutical compounds, corresponding to calorie restrictionRead more...
summary: presents an summary of present study aimed to go looking for life-extending medicines and describes pharmacological elements of anti-aging drugs. Readers are brought to the ancient heritage of geroprotection within the first bankruptcy. In-depth info on versions for investigating geroprotective medications precedes a bit protecting anti-aging houses of pharmaceutical compounds, resembling calorie restrict mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. eventually, concepts to translate discoveries from getting older examine into medicines and healthcare coverage views on anti-ageing drugs are supplied to provide an entire photograph of the sector
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Additional resources for Anti-aging drugs : from basic research to clinical practice
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Basisty, L. Gitari and P. S. Rabinovitch, Ageing Res. , 2015, 23, 101. E. Verdaguer, F. Junyent, J. Folch, C. Beas-Zarate, C. Auladell, M. Pallàs and A. Camins, Expert Opin. Drug Discovery, 2012, 7, 217. Y. Zhou and N. Huang, Methods Mol. , 2015, 1289, 13. S. M. Paul, D. S. Mytelka, C. T. Dunwiddie, C. C. Persinger, B. H. Munos, S. R. Lindborg and A. L. Schacht, Nat. Rev. Drug Discovery, 2010, 9, 203. A. A. Moskalev, A. M. Aliper, Z. Smit-McBride, A. Buzdin and A. Zhavoronkov, Cell Cycle, 2014, 13, 1063.
Madeo, Cell, 2014, 157, 1515. E. K. Quarles, D. F. Dai, A. Tocchi, N. Basisty, L. Gitari and P. S. Rabinovitch, Ageing Res. , 2015, 23, 101. E. Verdaguer, F. Junyent, J. Folch, C. Beas-Zarate, C. Auladell, M. Pallàs and A. Camins, Expert Opin. Drug Discovery, 2012, 7, 217. Y. Zhou and N. Huang, Methods Mol. , 2015, 1289, 13. S. M. Paul, D. S. Mytelka, C. T. Dunwiddie, C. C. Persinger, B. H. Munos, S. R. Lindborg and A. L. Schacht, Nat. Rev. Drug Discovery, 2010, 9, 203. A. A. Moskalev, A.
The two are, however, so interrelated as to make attempts relatively abortive. ” Rattan, 1991, “Although it is well known that most diseases show marked p. 526 46 increases with age, the connection between the ageing process and the incidence of age-related diseases is highly underestimated. ” Holliday, 1995, “…The distinction between so-called natural ageing and the patholp. 138 47 ogies that are common in old people is artificial. ” Callahan and “In short, not only does aging lend itself to be characterised as a Topinkova, disease, but the advantage of doing so is that, by rejecting the 1998, p.
Anti-aging drugs : from basic research to clinical practice by Alexander M Vaiserman (ed.)
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